ÌÇÐÄlogo

Start Time: 8:30 a.m.

Introduction

• Time: 8:30 - 8:35 a.m. (5 min)
• Presenter: Yingbin Fu, ÌÇÐÄlogo

Session 1: Cornea

• Time: 8:35 - 9:25 a.m. (50 min)
• Moderator: Elizabeth Zuniga-Sanchez, ÌÇÐÄlogo
  • The Importance of the Gut-Eye-Axis in Dry Eye – Cintia S. de Paiva, ÌÇÐÄlogo
  • A one dose siRNA therapeutic to promote regenerative healing in the cornea – Audrey M. Bernstein, SUNY Upstate Medical University

Break

• Time: 9:25 - 9:30 a.m. (5 min)

Session 2: Age-related Macular Degeneration

• Time: 9:30 - 10:45 a.m. (75 min)
• Moderator: Wei Li, ÌÇÐÄlogo
  • Using functional genomics to identify the mechanisms underlying age-related macular degeneration – Rinki Ratnapriya, ÌÇÐÄlogo
  • Adenosine receptor 2a in subretinal fibrosis – Yuqing Huo, ÌÇÐÄlogo
  • Mechanistic insight and treatment strategies for incomplete response to anti-VEGF therapies in AMD – Yingbin Fu, ÌÇÐÄlogo

Break

• Time: 10:45 - 10:50 a.m. (5 min)

Session 3: Glaucoma

• Time: 10:50 - 11:40 a.m. (50 min)
• Moderator: Rinki Ratnapriya, ÌÇÐÄlogo
  • Uncover Microglial Activation and Neuroinflammation as Root Causes of Glaucoma  â€“ Dongfeng Chen, Massachusetts Eye and Ear
  • Aberrant Wnt Signaling in the Pathogenesis of Glaucoma – Abbot Clark, University of North Texas Health Science Center

Lunch Break

• Time: 11:40 am - 12:10 p.m. (30 min)

Session 4: Keynote Presentation

• Time: 12:10 - 1:10 p.m. (60 min)
• Introduction: Samuel Wu, ÌÇÐÄlogo
• Speaker: Connie Cepko, Harvard Medical School & HHMI
• Topic: Gene-agnostic gene therapy to prolong vision

Break

• Time: 1:10 - 1:15 p.m. (5 min)

Session 5: Multiomics and Artificial Intelligence

• Time: 1:15 - 2:30 pm (75 min)
• Moderator: Rui Chen, University of California, Irvine
  • Integrating human genetics with regulatory and single cell genomics uncovers causal mechanisms for glaucoma – Ayellet Segrè, Massachusetts Eye and Ear
  • Type-specific features associated with retinal ganglion cell resilience and axon regeneration – Nicholas M. Tran, ÌÇÐÄlogo
  • Deep-Learning and Statistical Methods for Single-cell Data Analyses – Xu Dong, University of Missouri-Columbia

Break

• Time: 2:30 - 2:35 p.m. (5 min)

Session 6: Immune Cells and Inflammation

• Time: 2:35 - 3:50 p.m. (75 min)
• Moderator: Cintia S. de Paiva, ÌÇÐÄlogo
  • Immune cells: Unseen guardians of eye health and resilience – Daniel R. Saban, Duke University
  • Crystallin γS: A molecule expressed by microglia for retinal protection – Eleftherios Paschalis Ilios, Massachusetts Eye and Ear
  • Dry eye perturbs the balance between regulatory and inflammatory macrophages in the ocular surface – Stephen C. Pflugfelder, ÌÇÐÄlogo

Break

• Time: 3:50 - 3:55 p.m. (5 min)

Session 7: Retina

• Time: 3:55 - 5:35 pm (100 min)
• Moderator: Zheng Jiang and Samuel Wu, ÌÇÐÄlogo
  • Context-dependent motion processing by the retina – Wei Wei, University of Chicago
  • Circuit mechanisms in the retina shaping visual signaling at night – Jeffrey Diamond, NINDS
  • Electrophysiological profiling and classification of retinal ganglion cell subtypes in the mouse retina – Zheng Jiang, ÌÇÐÄlogo
  • Deciphering the developmental mechanisms of retinal circuit assembly – Elizabeth Zuniga-Sanchez, ÌÇÐÄlogo

Social Time

• Time: 5:35 - 6:35 p.m. (1 hour)