Positions
- Professor
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Pathology
ÌÇÐÄlogo
Houston, TX
- James R. Davis Chair
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ÌÇÐÄlogo
- Co-Director
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Cancer & Cell Biology Graduate Program
ÌÇÐÄlogo
- Director
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Comprehensive Mechanisms in Reproductive Sciences T32
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Education
- Post-Doctoral Fellowship at ÌÇÐÄlogo College Of Medicine
- 01/2007 - Houston, Texas, United States
- Reproductive Biology
- PhD from Northwestern University
- 04/2002 - Evanston, Illinois, United States
- Neurobiology and Physiology
- MS from Northwestern University
- 06/1995 - Evanston, Illinois, United States
- Biochemistry, Molecular Biology, and Cell Biology
- BA from Kent State University
- 06/1990 - Kent, Ohio, United States
- Anthropology and Sociology
Professional Interests
- Reproductive Biology
- Reproductive Cancers
Professional Statement
Our laboratory investigates the molecular mechanisms that regulate ovary development, and folliculogenesis, oocyte quality, female fertility, and reproductive aging, and how disruptions in these pathways contribute to reproductive diseases and gynecologic cancers.
We integrate genetically engineered mouse models with human genetics, transcriptomics, proteomics, and advanced imaging. Current research focuses on cell-signaling, post-translational modifications, mitochondrial function, and gene regulatory mechanisms that control oocyte development.
Our research is supported by the National Institutes of Health, including the Eunice K. Shriver National Institute of Child Health and Human Development (NICHD).
We integrate genetically engineered mouse models with human genetics, transcriptomics, proteomics, and advanced imaging. Current research focuses on cell-signaling, post-translational modifications, mitochondrial function, and gene regulatory mechanisms that control oocyte development.
Our research is supported by the National Institutes of Health, including the Eunice K. Shriver National Institute of Child Health and Human Development (NICHD).
Selected Publications
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Rodriguez A, Briley SM, Patton BK, Tripurani SK, Rajapakshe K, Coarfa C, Rajkovic A, Andrieux A, Dejean A, Pangas SA. " " Development. 2019 Dec 2; 146 (23)
Pubmed PMID: . -
Richards JS, Pangas SA. " " J. Clin. Invest.. 2010 Apr 1; 120 (4) : 963-72.
Pubmed PMID: . -
Middlebrook BS, Eldin K, Li X, Shivasankaran S, Pangas SA. " " Endocrinology. 2009 Dec ; 150 (12) : 5208-17.
Pubmed PMID: . -
Myers M, Middlebrook BS, Matzuk MM, Pangas SA. " " Dev. Biol.. 2009 Oct 15; 334 (2) : 458-67.
Pubmed PMID: .
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