Positions
- Postdoctoral Associate
-
Neuroscience
ÌÇÐÄlogo
Houston, TX, US
Addresses
- One ÌÇÐÄlogo Plaza (Lab)
-
Houston, TX, 77030
United States
Education
- PhD from ÌÇÐÄlogo
- 06/2021 - Houston, Texas, United States
- Developmental Biology
- BSc from Shanghai Jiao Tong University
- 07/2016 - Shanghai, China
- Biological Sciences
Professional Interests
- Neuron-glia interactions
- Myelin development and diseases
- Neuropsychiatric diseases
Professional Statement
I am a developmental neuroscientist and glial biologist fascinated by how neurons and glia interact to shape CNS development, homeostasis, and disease. The paranodal junction (PNJ), where a myelinating oligodendrocyte physically contacts an axon to form one of the largest intercellular adhesion structures in vertebrates, provides a uniquely well-defined and experimentally tractable system to address these questions. Disruption of the PNJ is a hallmark of neurological diseases such as multiple sclerosis (MS) and is increasingly implicated in aging, CNS injury, and psychiatric disorders, yet its molecular composition and regulation remain poorly understood.
My research integrates genetic, molecular, cellular, biochemical, physiological, behavioral, and multi-omic approaches with AAV-mediated in vivo genome editing in transgenic and disease models. Additionally, I take a highly collaborative and interdisciplinary approach, incorporating diverse model organisms and computational methods to address complex biological questions. Ultimately, by uncovering the fundamental biology of axon-glia interactions, I aim to inform future therapeutic strategies for neurological and psychiatric disorders.
My research integrates genetic, molecular, cellular, biochemical, physiological, behavioral, and multi-omic approaches with AAV-mediated in vivo genome editing in transgenic and disease models. Additionally, I take a highly collaborative and interdisciplinary approach, incorporating diverse model organisms and computational methods to address complex biological questions. Ultimately, by uncovering the fundamental biology of axon-glia interactions, I aim to inform future therapeutic strategies for neurological and psychiatric disorders.
Selected Publications
-
Yu Wu#, Xiaoyun Ding#, Jiaxing Li, Yueheng Xing, Babette Franke, Gabrielle R Brown, Victoria Rodriguez, … , Juan A Oses-Prieto, Taotao Tan, Lulu Shang, Alma L Burlingame, Daniel C Kraushaar, Ruth M Stassart, Matthew N Rasband (# equal contribution). " " J Neurosci. 2026 Aug 24;
Pubmed PMID: . -
X Ding, Y Ogawa, V Palfini, W Zhang, A Anderson, L Gancedo-Lopez, Z Liao, Z Yang, S Haddix, Y Xing, D Nguyen, J Curtis, D Church, Y Wu, A Jain, A Saltzman, J Oses-Prieto, M Torre, ..., A Burlingame, A Malovannaya, L Shang, P Liu, J Li, Y Gao, M Rasband. " " bioRxiv. 2026 Aug 23;
-
Xiaoyun Ding, Jackson R. Curtis, Yueheng Xing, Yu Wu, Elior Peles, Matthew N. Rasband. " " bioRxiv. 2025 Oct 21;
-
Xiaoyun Ding, Yu Wu, Anna Vainshtein, Victoria Rodriguez, Emily Ricco, James T. Okoh, Yanhong Liu, Daniel C. Kraushaar, Elior Peles, Matthew N. Rasband. " " Nat Commun. 2024 Dec 30; 15 (1) : 10865.
Memberships
- Society for Neuroscience
- Member (05/2025)
- American Society for Neurochemistry
- Student Member (02/2019)
- International Society for Neurochemistry
- Student Member (02/2019)
- Society for Developmental Biology
- Student Member (09/2017)
Funding
-
Pathway to Independence Award (K99/R00)
#1K99EY037780-01 - (04/15/2026 - 03/31/2031)
- National Institute of Health
-
Career Transition Fellowship
#NMSS-TA-2403-42997 - (07/01/2025 - 04/15/2026)
- National Multiple Sclerosis Society
to edit your profile